Bergamonte®

pill bottleBergamonte2014-M

The History of Bergamot

Bergamot (Citrus Bergamia Risso) is a citrus plant that grows almost exclusively in the narrow coastal Calabria region in Southern Italy, due to sensitivity to the weather and soil conditions. Bergamot juice was traditionally recognized by the local population as a remedy for supporting healthy cholesterol level and cardiovascular health. The medicinal use of bergamot, forgotten for decades, is now being rediscovered.

The juice and albedo of bergamot has a unique profile of flavonoid and glycosides, such as neoeriocitrin, neohesperidin, naringin, rutin, neodesmin, rhoifolin and poncirin. Naringin have been shown to be beneficial in animal models of atherosclerosis, while neoeriocitrin and rutin have been found to exhibit a strong capacity to prevent LDL from oxidation. Importantly, bergamot juice is rich in brutieridine and melitidine with an ability to inhibit HMG-CoA reductase.

 

Bergamonte2014-Fruit

 

Patented, Standardized, Clinically Tested

Bergamonte® contains bioactive compounds of extract of the juice and albedo of citrus bergamia risso, standardized to >30% polyphenolic flavanoids consisting of Naringin, Neohesperidin, Neoeriocitrin, 1% Melitidine, and 2% Brutieridine. Bergamonte® is produced using patented extraction technology through collaborative works of various Universities and research institutions in Italy.

At Nutri Lifescience, we believe in using only the finest quality and naturally pure ingredients to help our customer achieve extraordinary health and maintain longevity. We always strive for stringent quality control measures when choosing our ingredients. Our Nutri Bergamonte product is produced at a state of the GMP facility.
(US Patent: 20110223271)

 

Benefits of Bergamonte®

07_2_02 Cardiovascular Health
07_2_02 Supports Healthy Cholesterol*
07_2_02 Supports Healthy Blood Sugar
07_2_02 Possible Healthy Weight Management

* Already within the normal range

 

Citrus Bergamot Differs From C. Aurantium

Citrus Bergamot differs from C. Aurantium as Citrus Bergamot does not contain Synepherine, N-methyltyramine, and octopamine, which have been shown in research to constrict arteries, increase blood pressure, increase heart rate, cause heart-rhythm disorders, heart attack, and stroke.

Citrus Bergamot contains Melitidine and Brutieridine which is absent in C. Aurantuim. Research has shown that these compounds significantly supports healthy total cholesterol*, LDL, Triglycerides*, blood glucose levels, while increasing HDL.

 

How Citrus Bergamot Works

Citrus Bergamot works by blocking the HMG-CoA (3-hydroxy-3-methyglutaryl COA) reductase, an enzyme linked to the liver’s cholesterol production, thus inhibiting the liver’s ability to produce LDL.

These results in reduced cholesterol levels in liver cells, which then meet their cholesterol requirements by taking up cholesterol circulating in the blood, via a protein on the liver cell surface called an LDL receptor. LDL receptors break down the circulating cholesterol, which results in reduced levels of LDL cholesterol in the bloodstream, and a reduction in risk for high-cholesterol related diseases.

 

Hypolipemic and Hypoglycemic Activity of Bergamot Polyphenols

Source: Fitoterapia 82 (Nov 2011) 309–316
237 patients with hyperlipemia, hypercholesterolemic (HC, cLDL, low cHDL), mixed dyslipidemic (HC and TG), or metabolic syndrome (HC, HT, and HG) were taking either placebo, 500mg, 1000mg.

Bergamonte2014-Data-2

Serum asparate aminotransferase, alanine aminotransferase, creatine kinase, blood urea nitrogen and creatinine and blood cell counts all remain normal. Endothelial function was measured from brachial artery flow-mediated vasodilatation. Bergamonte group showed significantly improvement in vasodilation vs. no change in placebo.

The effect of Bergamonte® (500 and 1000 mg/daily) on reactive vasodilatation in patients suffering from isolated (HC) or mixed hyperlipidemia (HC/HT) and associated hyperglycemia (HC/HT /HG).

[Please note that the above research was based on those with metabolism syndrome without fatty liver group]

Bergamonte® helps support healthy total and LDL cholesterol levels (an effect accompanied by elevation of cHDL), triglyceride levels† and support healthy blood glucose. Moreover, Bergamonte® inhibited HMG-CoA reductase activity and enhances reactive vasodilation.

Maqui-Data-2

 

 

 

 

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